Health & Medical Kidney & Urinary System

Fibroepithelial Polyp of the Ureter

Fibroepithelial Polyp of the Ureter
A 73-year-old woman presented with asymptomatic gross hematuria. Her physical examination was unremarkable. A complete blood cell count, levels of serum electrolytes and creatinine, and results of cytologic evaluation of voided urine were normal. Urinalysis showed 0 to 2 white blood cells and 25 to 50 red blood cells per high-power field. Urine culture was negative.

An excretory urogram and left retrograde ureteropyelogram demonstrated a filling defect within the distal left ureter (Figures 1A and 1B). Cystourethroscopy revealed tissue visible within the left ureteral orifice (Figure 2). A biopsy was performed that demonstrated a fibroepithelial polyp (Figures 3A and 3B).


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Excretory urogram shows a filling defect in the distal left ureter (large white arrow). A malrotated ptotic right kidney (small straight arrows), clips from cholecystectomy (arrowheads), and pancreatic calcifications (curved arrows) are also shown.


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Left retrograde ureteropyelogram demonstrates filling defects throughout the distal left ureter.


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A branching polyp is observed in the distal left ureter adjacent to a guidewire.


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One of the lobulated projections of the fibroepithelial polyp shows benign urothelium covering a broad-based edematous fibrovascular stroma (hematoxylin-eosin, ×10).


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The fibroepithelial polyp is characterized by normal or hyperplastic urothelium overlying an intact basement membrane with extensive submucosal edema, dilated blood vessels, chronic inflammatory cells, and fibrous stroma (hematoxylin-eosin, ×40).

Which of the following is correct regarding fibroepithelial polyps?


  • A fibroepithelial polyp is a malignant neoplasm.

  • Pain is the most common presenting complaint of patients with fibroepithelial polyps.

  • Most fibroepithelial polyps occur in the upper ureter and ureteropelvic junction.

  • Malignant transformation of fibroepithelial polyps has not been reported.


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