How to Calculate Organic Extraction Yield
- 1). Determine the amount of product present in the crude mixture solution. The simplest analytical technique to determine the amount of product in the solution would be UV-Vis spectroscopy and Beer's law; however, depending on the contaminants and the product molecule, this may not be feasible.
- 2). Determine the amount of product captured after one washing of the crude solution by the extractant. Rotovapping off the solvent with a rotary evaporator can leave you with the product that can be easily massed.
- 3). Divide the amount of product captured by the extraction in grams by number of grams present in the crude solution. This will give you a percentage, which is the extraction yield.
