Melatonin has been touted as a remedy for jet lag. It's use is not without controversy, partly because some say that it is taken at too high a dose, or that it may not work for travelers suffering from jet lag. It has been used for sleep disorders, and is purported to mimic what's produced in the pineal gland (sometimes referred to as the third eye).

I haven't taken melatonin as one of the many jet lag remedies available, but there is a fair bit of information about it, and you can decide if it is a good option for you in your travels.

What is melatonin?
Melatonin is produced by the pineal gland, located approximately in the center of the brain. It is thought to serve as a signal that aids in regulating the circadian rhythm (sleep-wake cycle) by causing drowsiness. It also has a stimulating effect on the immune system, and has antioxidant properties, so its use isn't always related to sleep disorders.

The government site MedlinePlus gives melatonin a high rating, a grade A, for its use in treating jet lag: "Several human trials suggest that melatonin taken by mouth, started on the day of travel...and continued for several days, reduces the number of days required to establish a normal sleep pattern, diminishes the time it takes to fall asleep, improves alertness, and reduces daytime fatigue...the scientific evidence does suggest benefits of melatonin in up to half of people who take it for jet-lag."